A $528,000 grant will help researchers with the Peggy and Charles Stephenson Cancer Center at the University of Oklahoma explore a promising, new treatment for bladder cancer, the fourth most common cancer in men.
The Research Scholar Grant was awarded by the American Cancer Society to Youngjae You, Ph.D., a Cancer Center member and associate professor in the OU College of Pharmacy's Department of Pharmaceutical Sciences.
"Bladder cancer may be the fourth most common cancer in men, but it is the most expensive cancer to treat," You said, adding the reason it is so costly to treat is because current treatment requires frequent, follow-up exams utilizing cystoscopy.
Cystoscopy utilizes a slender, cylindrical instrument equipped with a small camera to examine the interior of the urinary bladder and also to introduce treatments there. However, current cystoscopy has some limitations, including difficulty in detecting small tumors.
You said the best way to reduce bladder cancer recurrence is sensitive detection and complete eradication at an early stage. He believes accomplishing this will require a therapy that combines fluorescence cystoscopic detection with photodynamic therapy.
If successful, the research would result in the development of improved options for the diagnosis and treatment of non-muscle, invasive bladder cancers.
You's principal OU Health Sciences Center collaborators in the research project are fellow Cancer Center members Dr. Sukyung Woo, also of the OU College of Pharmacy, and Dr. Robert Hurst, with the OU College of Medicine's Department of Urology.
"I am excited and honored to receive the Research Scholar Grant and grateful to the American Cancer Society for its generous support of our research," You said.
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